Recombinant FOXC1 antibody

Catalog No. ABIN7828213

This Rabbit Monoclonal antibody specifically detects FOXC1 in WB. It exhibits reactivity toward Human.

Quick Overview for Recombinant FOXC1 antibody (ABIN7828213)

Target: FOXC1 (Forkhead Box C1 (FOXC1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FOXC1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A663

Product Details anti-FOXC1 Antibody

Purpose: Recombinant FOXC1 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human FOXC1 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for FOXC1

Target: FOXC1 (Forkhead Box C1 (FOXC1))

Alternative Name: FOXC1

Background: IHG,FOXC,ASGD,FKHL,IRID,RIEG,FOXC1,ARA,ASGD3,FKHL7,FREAC-3,FREAC3,IGDA,IHG1,IRID1,RIEG3,FKH L7,FKHL 7,Forkhead (Drosophila) like 7,Forkhead box C1,Forkhead box protein C1,Forkhead drosophila homolog like 7,Forkhead like 7,Forkhead related activator 3,Forkhead related protein FKHL7,Forkhead related transcription factor 3,Forkhead-related protein FKHL7,Forkhead-related transcription factor 3,FOX C1,FOXC 1,FREAC 3,IHG 1,IRID 1,Iridogoniodysgenesis type 1,Myeloid factor delta,FoxC1, also named as FKHL7 or FREAC3, is one of two mammalian FoxC subfamily members. Along with FoxC2, it is expressed in paraxial mesoderm where it functions to promote somitogenesis, myogenesis, and vascular development, possibly under Wnt/β-catenin regulation. Mutations in FoxC1 are implicated in anterior segment dysgenesis (ASD) disorders, including congenital glaucoma and Axenfeld-Rieger syndrome. Research studies have shown that alterations in FoxC1 expression are linked to breast cancer invasiveness and have been shown to modulate proliferation and migration of breast cancer cells in vitro. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 70-74 kDa

Observed MW: 70 kDa The actual band is not consistent with the expectation.

UniProt: Q12948

Pathways: Chromatin Binding, Glycosaminoglycan Metabolic Process