Recombinant FOXL2 antibody

Catalog No. ABIN7828214

The Rabbit Monoclonal anti-FOXL2 antibody is suitable to detect FOXL2 in samples from Human, Mouse and Rat. It has been validated for WB and IHC.

Quick Overview for Recombinant FOXL2 antibody (ABIN7828214)

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FOXL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A225

Product Details anti-FOXL2 Antibody

Purpose: Recombinant FOXL2 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human FOXL2 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000,IHC 1:100-1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for FOXL2

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Alternative Name: FOXL2

Background: FOXL,Pfrk,Foxl2,Winged helix forkhead transcription factor 2 (FOXL2) promotes the proliferation and differentiation of granulosa cells by regulating the transcription of target genes, which is a key factor for ovarian differentiation and function maintenance. FOXL2 repels SOX9, Sertoli cells inhibit the transcription of SOX9 gene to prevent the transdifferentiation of the ovary to the testis, FOXL2 can also participate in the physiological regulation of endometrial tissue. Mutation of FOXL2 can cause small eyelid syndrome (BPES) and premature ovarian failure, so FOXL2 can be used as an important indicator of the prognosis and tumor progression of ovarian granulosa cell tumor, and it is also a specific marker of ovarian sex cord stromal tumor (SCST) Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 38 kDa

Observed MW: 50 kDa The actual band is not consistent with the expectation.

UniProt: O88470

Pathways: Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity