Recombinant GRP94 antibody

Catalog No. ABIN7828253

The Rabbit Monoclonal anti-GRP94 antibody is suitable to detect GRP94 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, IF and IP.

Quick Overview for Recombinant GRP94 antibody (ABIN7828253)

Target: GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This GRP94 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: A241

Product Details anti-GRP94 Antibody

Purpose: Recombinant GRP94 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human GRP94 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000,IHC 1:200-1:1000,IF 1:50,IP 1:25-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for GRP94

Target: GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))

Alternative Name: GRP94

Background: HEL,TRA,GRP,HSP90B,HSP90B1,ECGP,GP96,GRP94,HEL-S-125m,HEL35,TRA1,endoplasmin,ECGP,endoplasmin,GP96,GRP94,HEL35,HEL-S-125m,TRA1,90 kDa,94 kDa glucose regulated protein,94 kDa glucose-regulated protein,beta,Endothelial cell (HBMEC) glycoprotein,ENPL,ERp99,Glucose regulated protein 94 kDa,gp96 homolog,GRP 94,GRP-94,Heat shock protein,Heat shock protein 90 kDa beta member 1,heat shock protein 90 kDa beta (Grp94),Heat shock protein 90 kDa beta member 1,member 1,Stress inducible tumor rejection antigen GP96,tumor rejection antigen (gp96) 1,Tumor rejection antigen 1,Tumor rejection antigen gp96,Tumor rejection antigen-1 (gp96),Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion, the translocation process is mediated by the cargo receptor TMED10. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 94 kDa

Observed MW: 100 kDa The actual band is not consistent with the expectation.

UniProt: P14625

Pathways: Thyroid Hormone Synthesis, Activation of Innate immune Response, ER-Nucleus Signaling, Toll-Like Receptors Cascades