Recombinant Histone 3 antibody (meLys36)

Catalog No. ABIN7828271

The Rabbit Monoclonal anti-Histone 3 antibody is suitable to detect Histone 3 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, IF and IP.

Quick Overview for Recombinant Histone 3 antibody (meLys36) (ABIN7828271)

Target: Histone 3 (H3) (Histone H3 (H3))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Histone 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: A836

Product Details anti-Histone 3 Antibody

Binding Specificity: meLys36

Purpose: Recombinant Histone H3 (Mono Methyl Lys36) Monoclonal Antibody

Purification: Protein A purified

Immunogen: Monomethylated human histone H3 (Lys36) peptide

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000,IHC 1:100-1:500,IF 1:50,IP 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Histone 3

Target: Histone 3 (H3) (Histone H3 (H3))

Alternative Name: Histone H3

Background: Histone H,H3C,H3/A,H3C2,H3C3,H3C4,H3C6,H3C7,H3C8,H3FA,H3C10,H3C11,H3C12,HIST1H3A,H3C1,Histone H3.1,Histone H3/a,Histone H3/b,H3FL,HIST1H3B,H3FC,HIST1H3C,H3FB,HIST1H3D,H3FD,HIST1H3E,H3FI,HIST1H3F,H3FH,HIST1H3G,H3FK,HIST1H3H,H3FF,HIST1H3I,H3FJ,HIST1H3J,H3/A,H3FA,H3FB,H3FC,H3FD,H3FF,H3FH,H3FI,H3FJ,H3FK,H3FL,Hist1h3a,HIST1H3B,HIST1H3C,HIST1H3D,HIST1H3E,HIST1H3F,HIST1H3G,HIST1H3H,HIST1H3I,HIST1H3J,Histone H3.1,Histone H3/a,Histone H3/b,H3 histone family,H31,H3a,histone 1,Histone cluster 1,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l,member A,Histone post-translational modifications (PTMs) are key mechanisms of epigenetics that modulate chromatin structures, termed as ""histone code"". The PTMs on histone including acetylation, methylation, phosphorylation and novel acylations directly affect the accessibility of chromatin to transcription factors and other epigenetic regulators, altering genome stability, gene transcription, etc. Histone methylation occurs primarily at lysine and arginine residues on the amino terminal of core histones. Methylation of histones can either increase or decrease transcription of genes, depending on which amino acids (Lys or Arg) in the histones are methylated and how many methyl groups are attached (mono-, di-, Trimethylation on Lys, mono-di-symmetric/asymmetric methylation on Arg). Mostly, lysine methylation occurs primarily on histone H3 Lys4, 9, 27, 36, 79 and H4 Lys20, while Arginine methylation occurs primarily on histone H3 Arg2, 8, 17, 26 and H4 Arg3. histone methyltransferases (HMTs) and histone demethylases (HDMs) are major regulating factors. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 17 kDa

Observed MW: 17 kDa

UniProt: P68431