Recombinant ICOS antibody

Catalog No. ABIN7828304

The Rabbit Monoclonal anti-ICOS antibody is suitable to detect ICOS in samples from Human. It has been validated for IHC.

Quick Overview for Recombinant ICOS antibody (ABIN7828304)

Target: ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ICOS antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: A168

Product Details anti-ICOS Antibody

Purpose: Recombinant CD278/ICOS Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human CD278/ICOS fragment

Isotype: IgG, kappa

Application Details

Application Notes: IHC 1:200-1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for ICOS

Target: ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Alternative Name: CD278/ICOS

Background: CVID,ICOS,AILIM,CD278,CVID1,activation-inducible lymphocyte immunomediatory molecule,Inducible T-cell costimulator,Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: Q9Y6W8

Pathways: Cancer Immune Checkpoints