Recombinant CDH6 antibody

Catalog No. ABIN7828332

The Rabbit Monoclonal anti-CDH6 antibody (Clone A728) (ABIN7828332) specifically detects CDH6 in WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant CDH6 antibody (ABIN7828332)

Target: CDH6 (K-Cadherin (CDH6))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CDH6 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A728

Product Details anti-CDH6 Antibody

Purpose: Recombinant Cadherin-6 Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CDH6

Target: CDH6 (K-Cadherin (CDH6))

Alternative Name: Cadherin-6

Background: CAD,Cadherin 6 type,CADH,CAD6,CADH6,Cadherin 6,Cadherin 6 type 2,Cadherin 6 type 2 K cadherin (fetal kidney),Cadherin fetal kidney,Cadherin6,Cadherin-6,CDH 6,KCAD,K-Cadherin,Kidney Cadherin,CDH6,Cadherin-6, also known as kidney cadherin (K-Cadherin, CDH6) is a type II classical cadherin. While it was reported to have a tumor suppressor function in cholangiocarcinoma, cadherin-6 expression was shown to be a marker of epithelial mesenchymal transition, and positively correlated with stage and metastasis of papillary thyroid carcinoma. In related studies, cadherin-6 was shown to interact with GABARAP and related proteins to restrain autophagy, thereby promoting metastatic behavior. Cadherin-6 has since been proposed as an antibody-drug conjugate target for the treatment of ovarian and renal cancers. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 88 kDa

Observed MW: 130 kDa The actual band is not consistent with the expectation.

UniProt: P55285

Pathways: Cell-Cell Junction Organization