Recombinant LUM antibody

Catalog No. ABIN7828358

The Rabbit Monoclonal anti-LUM antibody is suitable to detect LUM in samples from Human, Rat and Mouse. It has been validated for WB.

Quick Overview for Recombinant LUM antibody (ABIN7828358)

Target: LUM (Lumican (LUM))

Antibody Type: Recombinant Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This LUM antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A552

Product Details anti-LUM Antibody

Purpose: Recombinant Lumican Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human Lumican fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for LUM

Target: LUM (Lumican (LUM))

Alternative Name: Lumican

Background: LUM,LDC,SLRR2D,lumican,Keratan Sulfate Proteoglycan Lumican,KSPG Lumican,Lumican precursor,Lumican (LUM), a member of the small leucine-rich proteoglycan (SLRP) family, is one of the major extracellular components in interstitial collagenous matrices of the corneal stroma, aorta, skin, skeletal muscle, lung, kidney, bone, cartilage, and intervertebral discs. SLRPs constitute an important fraction of noncollagenous extracellular matrix proteins and have important effects on cell behavior. Lumican regulates collagenous matrix assembly as a keratan sulfate proteoglycan in the cornea and may exist as a glycoprotein in the connective tissues of other organs. Posttranslational modifications lumican goes through can increase its apparent molecular weight to 50-90 kDa. Lumican participates in the maintenance of tissue homeostasis and modulates cellular functions including cell proliferation, migration, and differentiation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 38 kDa

Observed MW: 50-70 kDa The actual band is not consistent with the expectation.

UniProt: P51884

Pathways: Glycosaminoglycan Metabolic Process