Recombinant KDM2A antibody

Catalog No. ABIN7828363

This Rabbit Monoclonal antibody specifically detects KDM2A in WB, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Recombinant KDM2A antibody (ABIN7828363)

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This KDM2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: A401

Product Details anti-KDM2A Antibody

Purpose: Recombinant KDM2A Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human KDM2A fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:5000,IHC 1:50-1:100,IF 1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for KDM2A

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Alternative Name: KDM2A

Background: CXXC,FBXL,KIAA,FBL,KDM2A,CXXC8,FBL11,FBL7,FBXL11,JHDM1A,LILINA,lysine demethylase 2A,KIAA1004,CXXC8,FBL11,FBL7,FBXL11,JHDM1A,LILINA,lysine demethylase 2A,[Histone-H3]-lysine-36 demethylase 1A,CXXC-type zinc finger protein 8,F box / LRR repeat protein 11,F box and leucine rich repeat protein 11,F box protein FBL7,F-box and leucine-rich repeat protein 11,F-box protein FBL7,F-box protein Lilina,F-box/LRR-repeat protein 11,JmjC domain-containing histone demethylation protein 1A,Jumonji C domain containing histone demethylase 1A,Lysine (K) specific demethylase 2A,Lysine-specific demethylase 2A,Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and Trimethylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis. Regulates circadian gene expression by repressing the transcriptional activator activity of CLOCK-ARNTL/BMAL1 heterodimer and RORA in a catalytically-independent manner. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 133 kDa

Observed MW: 140 kDa The actual band is not consistent with the expectation.

UniProt: Q9Y2K7

Pathways: Warburg Effect