Recombinant Monoamine Oxidase A antibody

Catalog No. ABIN7828399

This Rabbit Monoclonal antibody specifically detects Monoamine Oxidase A in WB and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for Recombinant Monoamine Oxidase A antibody (ABIN7828399)

Target: Monoamine Oxidase A (MAOA)

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Monoamine Oxidase A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A611

Product Details anti-Monoamine Oxidase A Antibody

Purpose: Recombinant MAO-A Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human MAO-A fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Monoamine Oxidase A

Target: Monoamine Oxidase A (MAOA)

Alternative Name: MAO-A

Background: MAOA,BRNRS,MAO-A,Monoamine oxidase A (MAO-A), a mitochondrial enzyme, catalyzes the degradation of monoamines. Studies show that increased expression of MAO-A promotes prostate cancer metastasis by activating the Shh-IL6-RANKL signaling network. In addition, MAO-A expression in adipose tissue macrophages is upregulated in aging, leading to the reduction of noradrenaline availability in adipose tissue. Decreased levels of noradrenaline contribute to the aging-related decline of catecholamine-induced lipolysis in adipocytes. Furthermore, sympathetic neuron-associated macrophages import and degrade norepinephrine via the transporter SLC6A2 and MAO-A, respectively, and thus contribute to obesity. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 60 kDa

Observed MW: 60 kDa

UniProt: P21397