Recombinant NOS2 antibody

Catalog No. ABIN7828422

The Rabbit Monoclonal anti-NOS2 antibody (Clone A267) (ABIN7828422) specifically detects NOS2 in IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for Recombinant NOS2 antibody (ABIN7828422)

Target: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NOS2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: A267

Product Details anti-NOS2 Antibody

Purpose: Recombinant iNOS Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human iNOS fragment

Isotype: IgG, kappa

Application Details

Application Notes: IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for NOS2

Target: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Alternative Name: iNOS

Background: NOS,HEP-NOS,I-NOS,NOS2A,inducible,Inos,MAC-NOS,Inosl,Nitric oxide synthase,NOS type II,Nos2,Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P29477

Pathways: Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process