Recombinant OLR1 antibody

Catalog No. ABIN7828436

The Rabbit Monoclonal anti-OLR1 antibody is suitable to detect OLR1 in samples from Human. It has been validated for WB, FACS and IF.

Quick Overview for Recombinant OLR1 antibody (ABIN7828436)

Target: OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This OLR1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: A467

Product Details anti-OLR1 Antibody

Purpose: Recombinant OLR1/LOX1 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human OLR1/LOX1 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:5000,IF 1:50,FCM 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for OLR1

Target: OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))

Alternative Name: OLR1/LOX1

Background: OLR,Ox-LDL receptor,lectin-type oxidized LDL receptor,Oxidized low-density lipoprotein receptor,SLOX,SCARE,lectin-type oxidized LDL receptor 1,LOX-1,LOXIN,Oxidized low-density lipoprotein receptor 1,Ox-LDL receptor 1,SCARE1,SLOX1,CLEC8A,LOX1,OLR1,C-type lectin domain family 8 member A,hLOX 1,hLOX-1,Lectin like oxidized LDL receptor 1,Lectin like oxLDL receptor 1,Lectin type oxidized LDL receptor 1,Lectin-like oxidized LDL receptor 1,Lectin-like oxLDL receptor 1,low density lipoprotein oxidized,member 1,Ox LDL receptor 1,Oxidised low density lipoprotein (lectin like) receptor 1,Oxidized low density lipoprotein receptor 1,Oxidized low density lipoprotein receptor 1 soluble form,receptor 1,Scavenger receptor class E,soluble form,SR-EI,This protein is a low density lipoprotein receptor that belongs to the C-type lectin superfamily. It is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants. Diseases associated with OLR1 include Myocardial Infarction and Chlamydia Pneumonia. Among its related pathways are Innate Immune System and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and low-density lipoprotein particle receptor activity. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 31 kDa

Observed MW: 55 kDa The actual band is not consistent with the expectation.

UniProt: P78380