Recombinant PEG10 antibody

Catalog No. ABIN7828446

The Rabbit Monoclonal anti-PEG10 antibody (Clone A675) (ABIN7828446) specifically detects PEG10 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant PEG10 antibody (ABIN7828446)

Target: PEG10 (Paternally Expressed 10 (PEG10))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PEG10 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A675

Product Details anti-PEG10 Antibody

Purpose: Recombinant PEG10 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human PEG10 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for PEG10

Target: PEG10 (Paternally Expressed 10 (PEG10))

Alternative Name: PEG10

Background: PEG,RTL,Mart,RGAG,SIRH,KIAA,PEG10,EDR,HB-1,MEF3L,2-Mar,Mart2,RGAG3,RTL2,SIRH1,KIAA1051,MEF3L1,Paternally expressed gene 10(PEG10 ) is an imprinted gene which is derived from a Ty3/Gypsy long terminal repeat (LTR) retrotransposon family encoding Gag- and Pol-like domains. Deletion of PEG10 in mice leads to embryonic lethality due to defects in placental formation. PEG10 is aberrantly expressed in several cancer types, including hepatocellular carcinoma, and contributes to tumorigenesis by affecting cell proliferation, apoptosis, and metastasis. The PEG10 gene has two overlapping open reading frames that are regulated by the programmed process of -1 frameshifting. The first encoded protein ORF1 (or RF1) has a Gag domain with coiled-coil domain and zinc finger domains, while ORF1-2 (or RF1/RF2) is produced by -1 frameshifting and creates a fusion of the ORF1 Gag domain with a carboxyl-terminal Pol-like protease domain. PEG10 has retained the ability to form virus-like particles (VLPs) that are secreted as small extracellular vesicles delivered to distant sites. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 55/100 kDa

Observed MW: 55/100 kDa

UniProt: Q86TG7