Recombinant CD31 antibody (pTyr713)

Catalog No. ABIN7828464

The Rabbit Monoclonal anti-CD31 antibody (Clone A817) (ABIN7828464) specifically detects CD31 in WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant CD31 antibody (pTyr713) (ABIN7828464)

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD31 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A817

Product Details anti-CD31 Antibody

Binding Specificity: pTyr713

Purpose: Recombinant Phospho-CD31 (Tyr713) Monoclonal Antibody

Purification: Protein A purified

Immunogen: phosphorylated human CD31 (Tyr713) peptide

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD31

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Alternative Name: CD31

Background: PECA,cluster of differentiation,PECAM1,CD31,CD31/EndoCAM,GPIIA,PECA1,PECAM-1,endoCAM,cluster of differentiation 31,Platelet endothelial cell adhesion molecule,endocam,Adhesion molecule,CD31 antigen,CD31 EndoCAM,FLJ34100,FLJ58394,GPIIA',PECAM,Pecam 1,PECAM 1 CD31 EndoCAM,PECAM1,Platelet and endothelial cell adhesion molecule 1,Platelet/endothelial cell adhesion molecule 1,CD31,EndoCAM,GPIIA,PECA1,PECAM-1,Platelet endothelial cell adhesion molecule,CD31, also named as Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1), a member of the Ig superfamily of cell adhesion molecules, is expressed by circulating platelets, monocytes, neutrophils, some T cells, and endothelial cells and modulates cell adhesion, endothelial cell migration, and angiogenesis. CD31 is phosphorylated on Tyr686 at the cytoplasmic carboxy-terminal tail upon various stimuli (e.g. mechanical or oxidative stress), presumably by Src family members. The tyrosine phosphorylation mediates associations with a number of SH2 domain-containing binding partners such as PI3 kinase, SHIP, PLCγ, and SHP-2. Thus, CD31 serves as a scaffold for various signaling molecules. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 83 kDa

Observed MW: 130 kDa The actual band is not consistent with the expectation.

UniProt: P16284

Pathways: Regulation of Actin Filament Polymerization