Recombinant PCGF5 antibody

Catalog No. ABIN7828467

The Rabbit Monoclonal anti-PCGF5 antibody (Clone A765) (ABIN7828467) specifically detects PCGF5 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant PCGF5 antibody (ABIN7828467)

Target: PCGF5 (Polycomb Group Ring Finger 5 (PCGF5))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PCGF5 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A765

Product Details anti-PCGF5 Antibody

Purpose: Recombinant PCGF5 Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for PCGF5

Target: PCGF5 (Polycomb Group Ring Finger 5 (PCGF5))

Alternative Name: PCGF5

Background: RNF,Pcgf,RNF159,PCGF5,PCGF5 is the omponent of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.Within the PRC1-like complex, PCGF5 regulates RNF2 ubiquitin ligase activity. PCGF5 plays a redundant role with PCGF3 as part of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 30 kDa

Observed MW: 30 kDa

UniProt: Q86SE9