Recombinant PDHA1 antibody

Catalog No. ABIN7828508

The Rabbit Monoclonal anti-PDHA1 antibody is suitable to detect PDHA1 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for Recombinant PDHA1 antibody (ABIN7828508)

Target: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PDHA1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A520

Product Details anti-PDHA1 Antibody

Purpose: Recombinant PDHA1 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human PDHA1 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for PDHA1

Target: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Alternative Name: PDHA1

Background: PDHA1,PDHA,PDHAD,PDHCE1A,PHE1A,E1 alpha polypeptide 1,mitochondrial,ODPA,PDH,PDHE1 A type I,PDHE1-A type I,PDHα,Pyruvate Dehydrogenase (lipoamide) alpha 1,Pyruvate dehydrogenase complex,Pyruvate Dehydrogenase E1 alpha,Pyruvate dehydrogenase E1 component subunit alpha,somatic form,PDHA1, also named as PHE1A, is one of the 3 enzymes of the pyruvate dehydrogenase complex. It is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. Defects in PDHA1 are a cause of pyruvate dehydrogenase E1-alpha deficiency (PDHAD) and X-linked Leigh syndrome (X-LS). Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 43 kDa

Observed MW: 43 kDa

UniProt: P08559

Pathways: Warburg Effect