Recombinant ROCK2 antibody

Catalog No. ABIN7828528

This Rabbit Monoclonal antibody specifically detects ROCK2 in WB, IHC, IF and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Recombinant ROCK2 antibody (ABIN7828528)

Target: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ROCK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: A352

Product Details anti-ROCK2 Antibody

Purpose: Recombinant ROCK2 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human ROCK2 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:5000,IHC 1:50-1:100,IF 1:50,IP 1:25

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for ROCK2

Target: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Alternative Name: ROCK2

Background: KIAA,Rho kinase,Rho-associated protein kinase,ROCK2,ROCK-II,Rho kinase 2,Rho-associated,Rho-associated protein kinase 2,ROCK 2,Rock II,Rock2m,ROK alpha,ROKalpha,KIAA0619,B230113H15Rik,coiled coil containing protein kinase II,coiled-coil-containing protein kinase 2,mKIAA0619,p164 ROCK 2,p164 ROCK-2,Rho associated,Rho associated coiled coil containing protein kinase 2,Rho associated protein kinase 2,Rho-kinase,Rho associated coiled-coil containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene. Fasudil is an inhibitor of ROCK protein.The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 160 kDa

Observed MW: 190-200 kDa The actual band is not consistent with the expectation.

UniProt: O75116

Pathways: Microtubule Dynamics, WNT Signaling, Tube Formation