Recombinant SPR antibody

Catalog No. ABIN7828553

The Rabbit Monoclonal anti-SPR antibody is suitable to detect SPR in samples from Human. It has been validated for WB and IHC.

Quick Overview for Recombinant SPR antibody (ABIN7828553)

Target: SPR (Sepiapterin Reductase (SPR))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SPR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A748

Product Details anti-SPR Antibody

Purpose: Recombinant SPR Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000,IHC 1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for SPR

Target: SPR (Sepiapterin Reductase (SPR))

Alternative Name: SPR

Background: SDR38C,member,OTTHUMP,SPR,SDR38C1,8 dihydrobiopterin:NADP+ oxidoreductase),member 1,OTTHUMP00000160199,Sepiapterin reductase,Sepiapterin reductase (7,Short chain dehydrogenase/reductase family 38C,SPRE,SPR can catalyze the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.Defects in SPR are the cause of dystonia DOPA-responsive due to sepiapterin reductase deficiency (DRDSPRD). In the majority of cases, patients manifest progressive psychomotor retardation, dystonia and spasticity. Cognitive anomalies are also often present. The disease is due to severe dopamine and serotonin deficiencies in the central nervous system caused by a defect in BH4 synthesis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 28 kDa

Observed MW: 27 kDa The actual band is not consistent with the expectation.

UniProt: P35270

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration