Recombinant SETD1A antibody

Catalog No. ABIN7828559

The Rabbit Monoclonal anti-SETD1A antibody is suitable to detect SETD1A in samples from Human, Mouse and Rat. It has been validated for IHC, IF and FACS.

Quick Overview for Recombinant SETD1A antibody (ABIN7828559)

Target: SETD1A (SET Domain Containing 1A (SETD1A))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SETD1A antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: A256

Product Details anti-SETD1A Antibody

Purpose: Recombinant SETD1A Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human SETD1A fragment

Isotype: IgG, kappa

Application Details

Application Notes: IHC 1:50-1:100,IF 1:100-1:500,FCM 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for SETD1A

Target: SETD1A (SET Domain Containing 1A (SETD1A))

Alternative Name: SETD1A

Background: Set,KIAA,Set1,KMT2F,Set1A,SETD1A,KIAA0339,Histone-lysine N-methyltransferase SETD1A,hSET1A,KMT2F,Lysine N methyltransferase 2F,Lysine N-methyltransferase 2F,SET domain containing 1A,SET domain containing protein 1A,SET domain-containing protein 1A,SET1,Set1 Ash2 histone methyltransferase complex subunit SET1,Set1/Ash2 histone methyltransferase complex subunit SET1,SET1A,hSET1 is a component of the histone methyltransferase (HMT) complex, which is a member of the COMPASS family, has H3K4 methyltransferase activity, and is closely related to development and tumors. hSET1 can produce mono-, di- and Trimethylation at lys4 (K4) on histone H3. This activity is blocked by the pre-methylation of the transcription repressor K9, indicating that the SET1/ASH2 complex can cause crosstalk between K9 methylation and K4 methylation. SET1 protein may play a role in synaptic function and neuron development. In addition, hSET1 protein can affect the proliferation and apoptosis of leukemia cells, and promote differentiation into neutrophils, providing new ideas for the treatment of leukemia and other cancers. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: O15047