Recombinant SF3B3 antibody

Catalog No. ABIN7828581

The Rabbit Monoclonal anti-SF3B3 antibody (Clone A553) (ABIN7828581) specifically detects SF3B3 in WB, IHC and IP. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant SF3B3 antibody (ABIN7828581)

Target: SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SF3B3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: A553

Product Details anti-SF3B3 Antibody

Purpose: Recombinant SF3B3 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human SF3B3 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:500-1:2000,IP 1:25

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for SF3B3

Target: SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))

Alternative Name: SF3B3

Background: SAP,SF3B,KIAA,Splicing factor 3B subunit,Spliceosome-associated protein,Spliceosome-associated protein 130,Splicing factor 3B subunit 3,SF3B3,KIAA0017,SAP130,Pre mRNA splicing factor SF3b 130 kDa subunit,Pre-mRNA-splicing factor SF3b 130 kDa subunit,RSE1,SAP 130,SF3b130,SF3B3_HUMAN,Spliceosome associated protein 130,Splicing factor 3b subunit 3 130kD,STAF130,SF3B3 is one of four proteins for SF3B, which is involved in RNA splicing. Introns are removed from nuclear pre-mRNA in 2-step transesterification reactions. Splicing occurred in a large ribonucleoprotein particle, called the spliceosome. Spliceosomal intermediate complexes form on pre-mRNA in the order E, A, B, and C, with the catalytic reactions occurring in complex C. U2 small nuclear ribonucleoproteins are one of the proteins essential for spliceosome assembly and mRNA splicing. Functional U2 snRNP is composed of a 12S unit and 2 splicing factors, SF3A, which is composed of 3 proteins, and SF3B, which composed of 4 proteins. SF3B3 is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence(BPS) in pre-mRNA. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 135 kDa

Observed MW: 135 kDa

UniProt: Q15393