Recombinant SOX17 antibody

Catalog No. ABIN7828584

The Rabbit Monoclonal anti-SOX17 antibody (Clone A676) (ABIN7828584) specifically detects SOX17 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant SOX17 antibody (ABIN7828584)

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SOX17 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A676

Product Details anti-SOX17 Antibody

Purpose: Recombinant SOX17 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human SOX17 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:2000,IHC 1:100-1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for SOX17

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Alternative Name: SOX17

Background: VUR,SOX,VUR3,SOX17,SRY-related high mobility group box (SOX) proteins comprise a large family of widely conserved transcription factors. SOX proteins do not directly mediate transcription, but require binding partners that regulate their ability to mediate transcription of target genes that control cell fate determination and development .Transcription factor Sox17 is a Sox family protein with an established role in endoderm specification during development. In addition, Sox17 plays essential roles in the maintenance of the hematopoietic stem cell pool and for vascular morphogenesis during development. Sox17 negatively regulates oligodendrocyte precursor differentiation by antagonizing β-catenin signaling. Mutation in the correspondingSox17gene in humans is associated with a form of vesicoureteral reflux, a disorder characterized by congenital kidney and urinary tract defects. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 55 kDa

Observed MW: 55 kDa

UniProt: Q9H6I2