Recombinant tau antibody (pSer199)

Catalog No. ABIN7828616

The Rabbit Monoclonal anti-tau antibody is suitable to detect tau in samples from Human, Mouse and Rat. It has been validated for WB, IHC, IF and FACS.

Quick Overview for Recombinant tau antibody (pSer199) (ABIN7828616)

Target: tau (tau Protein)

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This tau antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: A803

Product Details anti-tau Antibody

Binding Specificity: pSer199

Purpose: Recombinant Phospho-Tau (Ser199) Monoclonal Antibody

Purification: Protein A purified

Immunogen: phosphorylated human Tau (Ser199) peptide

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:3000,IHC 1:200-1:1000,IF 1:50,FCM 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for tau

Target: tau (tau Protein)

Alternative Name: Tau

Background: FTDP,PPP1R,DDPAC,FTDP-17,MAPTL,MSTD,MTBT1,MTBT2,PPND,PPP1R103,TAU,MAPT,Microtubule-Associated Protein Tau,Neurofibrillary Tangle Protein,Paired Helical Filament-Tau,PHF-Tau,pMAPT/pTAU,TAU and MAPT,N/A,AI413597,AW045860,FLJ31424,FTDP 17,G protein beta1/gamma2 subunit interacting factor 1,included,MGC134287,MGC138549,MGC156663,Microtubule associated protein tau,Microtubule associated protein tau isoform 4,Mtapt,Paired helical filament tau,PHF tau,Protein phosphatase 1,pTau,regulatory subunit 103,RNPTAU,Tauopathy and respiratory failure,Promotes microtubule assembly and stability and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 79 kDa

Observed MW: 55 kDa The actual band is not consistent with the expectation.

UniProt: P10636