Recombinant tau antibody (pSer262)

Catalog No. ABIN7828617

The Rabbit Monoclonal anti-tau antibody (Clone A408) (ABIN7828617) specifically detects tau in WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant tau antibody (pSer262) (ABIN7828617)

Target: tau (tau Protein)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This tau antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A408

Product Details anti-tau Antibody

Binding Specificity: pSer262

Purpose: Recombinant Phospho-Tau (S262) Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human Tau (phospho S262) fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for tau

Target: tau (tau Protein)

Alternative Name: Tau

Background: FTDP,PPP1R,DDPAC,FTDP-17,MAPTL,MSTD,MTBT1,MTBT2,PPND,PPP1R103,TAU,MAPT,Microtubule-Associated Protein Tau,Neurofibrillary Tangle Protein,Paired Helical Filament-Tau,PHF-Tau,pMAPT/pTAU,TAU and MAPT,N/A,AI413597,AW045860,FLJ31424,FTDP 17,G protein beta1/gamma2 subunit interacting factor 1,included,MGC134287,MGC138549,MGC156663,Microtubule associated protein tau,Microtubule associated protein tau isoform 4,Mtapt,Paired helical filament tau,PHF tau,Protein phosphatase 1,pTau,regulatory subunit 103,RNPTAU,Tauopathy and respiratory failure,Tau is a neuronal microtubule-associated protein, which is mainly located in the cytoplasm, cytoskeleton and cell membrane. Tau is expressed in neuronal tissues and exists in the form of a variety of alternate splicing subtypes. Its C-terminus is combined with axon microtubules, and the N-terminus is combined with neuroplasmic membrane components to maintain the stability and plasticity of the neuronal cytoskeleton. In neurons, hyperphosphorylated and abnormally glycosylated Tau protein accumulates, causing neurofibrosis and neurodegeneration, such as Alzheimer's disease (AD), frontotemporal dementia, and chronic traumatic encephalopathy (CTE), Parkinson's disease after encephalitis, etc. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 79 kDa

Observed MW: 50 kDa The actual band is not consistent with the expectation.

UniProt: P10636