Recombinant Thyroglobulin antibody

Catalog No. ABIN7828625

The Rabbit Monoclonal anti-Thyroglobulin antibody is suitable to detect Thyroglobulin in samples from Human. It has been validated for IHC and FACS.

Quick Overview for Recombinant Thyroglobulin antibody (ABIN7828625)

Target: Thyroglobulin (TG)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Thyroglobulin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: A378

Product Details anti-Thyroglobulin Antibody

Purpose: Recombinant Thyroglobulin Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human Thyroglobulin fragment

Isotype: IgG, kappa

Application Details

Application Notes: IHC 1:100-1:1000,FCM 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Thyroglobulin

Target: Thyroglobulin (TG)

Alternative Name: Thyroglobulin

Background: TDH,TG,AITD3,TGN,AITD 3,hTG,TDH3,THYG,Thyroglobulin,AITD 3,AITD3,hTG,TDH3,Tg,TGN,THYG,Thyroglobulin,Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P01266

Pathways: Thyroid Hormone Synthesis