Recombinant TOP3B antibody

Catalog No. ABIN7828629

The Rabbit Monoclonal anti-TOP3B antibody (Clone A690) (ABIN7828629) specifically detects TOP3B in WB and IF. The antibody is reactive with Human samples.

Quick Overview for Recombinant TOP3B antibody (ABIN7828629)

Target: TOP3B (Topoisomerase (DNA) III beta (TOP3B))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TOP3B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: A690

Product Details anti-TOP3B Antibody

Purpose: Recombinant TOP3B Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:2000,IF 1:100-1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for TOP3B

Target: TOP3B (Topoisomerase (DNA) III beta (TOP3B))

Alternative Name: TOP3B

Background: TOP3B,TOP3B1,DNA topoisomerase 3-beta-1(TOP3B), an enzyme that controls and alters the topologic states of DNA during transcription. TOP3B catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. TOP3B interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of TOP3B may be related to higher survival rates in breast cancer patients. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 97 kDa

Observed MW: 97 kDa

UniProt: O95985