Recombinant TUBB3 antibody

Catalog No. ABIN7828648

This Rabbit Monoclonal antibody specifically detects TUBB3 in WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Recombinant TUBB3 antibody (ABIN7828648)

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TUBB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A651

Product Details anti-TUBB3 Antibody

Purpose: Recombinant beta III Tubulin Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human beta III Tubulin fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000,IHC 1:200-1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Alternative Name: beta III Tubulin

Background: FEOM,beta,CFEOM,CDCBM,CDCBM1,CFEOM3,CFEOM3A,FEOM3,TUBB4,beta-4,beta Tubulin III,TUBB3,beta 3 tubulin,M(beta)3,M(beta)6,MC1R,Neuron specific beta III Tubulin,Neuron-specific class III beta-tubulin,QccE-11995,QccE-15186,TBB3,Tubb 3,Tubulin beta 3,Tubulin beta 3 chain,Tubulin beta 4,Tubulin beta III,Tubulin beta-3 chain,Tubulin beta-4 chain,Tubulin beta-III,Beta III Tubulin (TUBB3) is one of six β-tubulin isoforms and is expressed highly during fetal and postnatal development (axon guidance and maturation). Its expression levels decrease in the adult central nervous system (CNS) but remain high in the peripheral nervous system (PNS). Microtubules enriched in β3-tubulin are more dynamic than those composed of other β-tubulin isoforms. Research studies have shown that mutations in the β3-tubulin gene TUBB3 cause ocular motility defects and other nervous system disorders. Furthermore, β3-tubulin is present in neoplastic but not in normal differentiated glial cells. Thus, β3-tubulin is a great neuronal marker. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 50 kDa

Observed MW: 50 kDa

UniProt: Q13509

Pathways: Microtubule Dynamics, M Phase