Recombinant UQCRFS1 antibody

Catalog No. ABIN7828656

The Rabbit Monoclonal anti-UQCRFS1 antibody (Clone A596) (ABIN7828656) specifically detects UQCRFS1 in WB, IHC and IP. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant UQCRFS1 antibody (ABIN7828656)

Target: UQCRFS1 (Ubiquinol-Cytochrome C Reductase, Rieske Iron-Sulfur Polypeptide 1 (UQCRFS1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This UQCRFS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: A596

Product Details anti-UQCRFS1 Antibody

Purpose: Recombinant UQCRFS1/RISP Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human UQCRFS1/RISP fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:5000,IHC 1:200-1:1000,IP 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for UQCRFS1

Target: UQCRFS1 (Ubiquinol-Cytochrome C Reductase, Rieske Iron-Sulfur Polypeptide 1 (UQCRFS1))

Alternative Name: UQCRFS1/RISP

Background: RIS,RIP,UQCR,UQCRFS,UQCRFS1,RIP1,RIS1,RISP,UQCR5,Ubiquinol-cytochrome c reductase iron-sulfur subunit (UQCRFS1), also known as Rieske iron-sulfur protein (RISP), is a component of Complex III in the mitochondrial electron transport chain. UQCRFS1/RISP and two other subunits, cytochrome b (MT-CYB) and cytochrome c1 (CYC1), are essential for the catalytic activity of Complex III. Studies show that UQCRFS1/RISP is required for fetal mouse hematopoietic stem cell differentiation and adult mouse hematopoietic stem cell quiescence. In addition, loss of UQCRFS1/RISP decreases the strength of T cell receptor (TCR) signaling, indicating that this protein is critical for optimal TCR signaling. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 30 kDa

Observed MW: 25 kDa The actual band is not consistent with the expectation.

UniProt: P47985

Pathways: Proton Transport