Recombinant WT1 antibody

Catalog No. ABIN7828676

The Rabbit Monoclonal anti-WT1 antibody is suitable to detect WT1 in samples from Human, Rat and Mouse. It has been validated for IHC and WB.

Quick Overview for Recombinant WT1 antibody (ABIN7828676)

Target: WT1 (Wilms Tumor 1 (WT1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This WT1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: A742

Product Details anti-WT1 Antibody

Purpose: Recombinant WT1 Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:2000-1:10000,IHC 1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for WT1

Target: WT1 (Wilms Tumor 1 (WT1))

Alternative Name: WT1

Background: AWT,FWT,NPHS,EWS-WT,WIT,WT1,AWT1,EWS-WT1,GUD,NPHS4,WAGR,WIT-2,WT33,FWT1,Wilms Tumor,Wilms tumor 1,Wilms' tumor gene,Wilms tumor protein,Wilms' tumor protein,WIT 2,WIT2,WT,WT 1,WIT 2, WT 1,AWT1,FWT1,GUD,NPHS4,WAGR,Wilms tumor 1,Wilms Tumor,Wilms tumor protein,Wilms' tumor gene,Wilms' tumor protein,WIT2,WT,WT1,WT1,WT33,Wilms' Tumor protein (WT1) is a transcription factor named from Wilms' Tumor 1, an embryonal malignancy of the kidneys that is caused by mutations in the WT1 gene. It is highly important in development, particularly of the genitourinary system, and mutations and dysregulation of expression of WT1 result in a variety of syndromes affecting the genitourinary system and other tissues.WT1 has a myriad of biological functions and a host of interacting partners and target genes. It can behave as a transcriptional activator, or a repressor, and can act as an oncogene or a tumor suppressor. It exerts influence over the epigenetic landscape, and also has post translational influence of gene expression through RNA interactions. The diverse biological roles of WT1 have been attributed to the existence of multiple isoforms and post translation modifications of the protein. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 49 kDa

Observed MW: 52 kDa The actual band is not consistent with the expectation.

UniProt: P19544

Pathways: Tube Formation