CD8 alpha antibody (APC-Cy7)

Catalog No. ABIN7828712

The Mouse Monoclonal anti-CD8 alpha antibody is suitable to detect CD8 alpha in samples from Human. It has been validated for FACS.

Quick Overview for CD8 alpha antibody (APC-Cy7) (ABIN7828712)

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD8 alpha antibody is conjugated to APC-Cy7

Application: Flow Cytometry (FACS)

Clone: HIT8a

Product Details anti-CD8 alpha Antibody (APC-Cy7)

Purpose: APC/Cyanine 7 Anti-Human CD8a Antibody[HIT8a]

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Control: E-AB-F09792N

Restrictions: For Research Use only

Handling

Concentration: 5 μL/tests

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer.

Handling Advice: Please protected from prolonged exposure to light and do not freeze

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for CD8 alpha

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Alternative Name: CD8a

Background: T-cell surface glycoprotein CD8 alpha chain,CD8A,T8,Leu2,MAL,CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck. Cat.No. Product Name Sizes E-CK-A105 10xACK Lysis Buffer 500 mL , 200 mL , 100 mL E-CK-A107 Cell Staining Buffer 500 mL , 200 mL , 100 mL Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Gene ID: 925

UniProt: P01732

Pathways: TCR Signaling