CD51 antibody

Catalog No. ABIN7828788

The Rat Monoclonal anti-CD51 antibody (Clone RMV-7) (ABIN7828788) specifically detects CD51 in FACS. The antibody is reactive with Mouse samples.

Quick Overview for CD51 antibody (ABIN7828788)

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD51 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: RMV-7

Product Details anti-CD51 Antibody

Purpose: Purified Anti-Mouse CD51 Antibody[RMV-7]

Purification: >98%, Protein A/G purified

Purity: >98 %

Immunogen: Recombinant MouseCD51 protein

Isotype: IgG1, kappa

Application Details

Application Notes: FCM 2 μg/mL(0.5x106-1x106 cells)

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.05 % non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD51

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Alternative Name: CD51

Background: Integrin alpha-V;Integrin αV chain;Vitronectin Receptor;αV integrin;Itgav;vitronectin R;integrin &alpha-V-V,CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αv integrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P43406

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex