2B4 antibody

Catalog No. ABIN7828847

The Mouse Monoclonal anti-2B4 antibody is suitable to detect 2B4 in samples from Human. It has been validated for FACS.

Quick Overview for 2B4 antibody (ABIN7828847)

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This 2B4 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: C1-7

Product Details anti-2B4 Antibody

Purpose: Purified Anti-Human CD244 Antibody[C1.7]

Purification: >98%, Protein A/G purified

Purity: >98 %

Immunogen: Recombinant Human CD244 protein

Isotype: IgG1, kappa

Application Details

Application Notes: FCM 2 μg/mL(0.5x106-1x106 cells)

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.05 % non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for 2B4

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Alternative Name: CD244

Background: 2B4,C9.1,CD244 antigen,CD244 Molecule,CD244 Molecule natural killer cell receptor 2B4,CD244 natural killer cell receptor 2B4,F730046O15Rik,Ly90,member 4,Natural killer cell activation-inducing ligand,NK cell activation inducing ligand,NK cell activation inducing ligand NAIL,NK cell type I receptor protein 2B4,Non-MHC restricted killing associated,OTTHUMP00000027884,p38,signaling lymphocytic activation molecule 4,SLAM family,h2B,SLAM family member,Natural killer cell receptor 2B,NKR2B,SLAMF,CD244,2B4,NAIL,NKR2B4,Nmrk,SLAMF4,h2B4,Natural killer cell receptor 2B4,NK cell activation-inducing ligand,SLAM family member 4,CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including most CD8+ T cells and γ/δ T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: Q9BZW8