NOS2 antibody (PE)

Catalog No. ABIN7828919

The Rat Monoclonal anti-NOS2 antibody is suitable to detect NOS2 in samples from Mouse. It has been validated for ICFC.

Quick Overview for NOS2 antibody (PE) (ABIN7828919)

Target: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This NOS2 antibody is conjugated to PE

Application: Intracellular Flow Cytometry (ICFC)

Clone: W16030C

Product Details anti-NOS2 Antibody (PE)

Purpose: PE Anti-Mouse Nos2(iNos) Antibody[W16030C]

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Control: E-AB-F09842D

Restrictions: For Research Use only

Handling

Concentration: 5 μL/tests

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer.

Handling Advice: Please protected from prolonged exposure to light and do not freeze

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for NOS2

Target: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Alternative Name: Nos2

Background: Nitric oxide synthase 2,nitric oxide synthase 2A,NOS2A,HEP-NOS,inducible nitric oxide synthase (iNOS),Nitric oxide synthase,inducible,Inducible NOS,Nitric Oxide Synthase 2 (NOS2), also known as inducible NOS (iNOS), contains an N-terminal oxygenase domain and a C-terminal reductase domain, and functions to catalyze the formation of nitric oxide (NO) from L-arginine. NO is a reactive free radical which acts as a biologic messenger with diverse functions throughout the body, such as neurotransmission, antimicrobial, and antitumor activity. NOS2 is involved in inflammatory responses and enhances the synthesis of PGE2 and proinflammatory cytokines such as IL-6 and IL-8. The NOS2 gene is highly expressed in liver and is inducible by a combination of bacterial endotoxins and certain cytokines, including IL-1, IFNγ and TNFα. NOS2 also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such as COX2. Cat.No. Product Name Sizes E-CK-A105 10xACK Lysis Buffer 500 mL , 200 mL , 100 mL E-CK-A107 Cell Staining Buffer 500 mL , 200 mL , 100 mL E-CK-A109 Intracellular Fixation/Permeabilization Buffer Kit 500Assays , 100Assays , 50Assays Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Gene ID: 4843

UniProt: P29477

Pathways: Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process