DLK1
Reactivity: Human
WB, ELISA, FACS
Host: Rat
Polyclonal
unconjugated
Application Notes
Flow Cyt 1/100
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Please see Certificate of Analysis for specific instructions of reconstitution.
Buffer
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Storage
-20 °C,-80 °C
Storage Comment
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).
Expiry Date
12 months
Target
DLK1
(delta-Like 1 Homolog (Drosophila) (DLK1))
Alternative Name
DLK1
Background
This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal. [provided by RefSeq, Nov 2015]