Neuropilin 1 antibody

Catalog No. ABIN7829662

This Rabbit Monoclonal antibody specifically detects Neuropilin 1 in FACS. It exhibits reactivity toward Human.

Quick Overview for Neuropilin 1 antibody (ABIN7829662)

Target: Neuropilin 1 (NRP1)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Neuropilin 1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 1F11

Product Details anti-Neuropilin 1 Antibody

Purpose: Anti-NRP1 antibody(1F11), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Application Details

Application Notes: Flow Cyt 1/100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Expiry Date: 12 months

Target Details for Neuropilin 1

Target: Neuropilin 1 (NRP1)

Alternative Name: NRP1

Background: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells. [provided by RefSeq, Nov 2020]

UniProt: O14786

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals