alpha Fetoprotein antibody (HRP)
Quick Overview for alpha Fetoprotein antibody (HRP) (ABIN7830276)
Target
See all alpha Fetoprotein (AFP) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-alpha-Fetoprotein HRP
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Characteristics
- The mouse monoclonal antibody AFP-01 reacts with human alpha-Fetoprotein (AFP), a 70 kDa oncofetal antigen. AFP is a major fetal plasma protein, but is not present in healthy adult tissues. Elevated AFP concentrations in adult plasma may be an early marker of hepatocellular carcinoma or teratoblastoma, while high concentrations in amniotic fluid may indicate severe congenital defects of a fetus.
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Purification
- Purified antibody is conjugated with activated horseradish peroxidase (HRP) of high specific enzyme activity under optimum conditions and unconjugated antibody and free HRP are removed by size-exclusion chromatography.
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Immunogen
- purified alpha-Fetoprotein
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Isotype
- IgG1
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Application Notes
- ELISA: The antibody AFP-01 has been tested as the detection antibody in a sandwich ELISA for analysis of human alpha-fetoprotein in combination with antibody AFP-11 (ABIN93887).
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 0.01 % thimerosal
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Do not freeze,Protect from prolonged exposure to light
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Storage
- 4 °C
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Storage Comment
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
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Alternative Name
- alpha-Fetoprotein
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Background
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NCBI Full Gene Name: alpha fetoprotein
Other names: AFP, FETA, HPAFP
Gene name: AFP
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Gene ID
- 174
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UniProt
- P02771
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Pathways
- C21-Steroid Hormone Metabolic Process
Target
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