GLO1 antibody

Catalog No. ABIN7833275

The Rat Monoclonal anti-GLO1 antibody (Clone 6F10) (ABIN7833275) specifically detects GLO1 in WB, ELISA and IF. The antibody is reactive with Human, Mouse and Monkey samples.

Quick Overview for GLO1 antibody (ABIN7833275)

Target: GLO1 (Glyoxalase I (GLO1))

Reactivity: Human, Mouse, Monkey

Host: Rat

Clonality: Monoclonal

Conjugate: This GLO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 6F10

Product Details anti-GLO1 Antibody

Purpose: Anti-GLO1 | Glyoxalase I (clone 6F10)

Cross-Reactivity (Details): Human, simian, mouse

Sterility: Sterile filtered

Immunogen: Recombinant

Isotype: IgG2b kappa

Application Details

Application Notes: 1 : 1000 (WB)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Proprietary affinity chromatography in PBS. Contains 50 % glycerol, filter sterilized.

Handling Advice: Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube

Storage: -20 °C

Storage Comment: Store at -20°C, make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Target Details for GLO1

Target: GLO1 (Glyoxalase I (GLO1))

Alternative Name: GLO1

Background: Glyoxalase I (GLO1) is an enzyme that plays a role in the detoxification of methylglyoxal (MG), a side-product of glycolysis, via condensation with glutathione to produce S-lactoyl-glutathione. GLO1 is a zinc metalloenzyme whose crystal structure has been solved. The bacterial and yeast enzymes are monomeric while the mammalian one is homodimeric and its sequence is well conserved. GLO1 is found over-expressed in some tumors. GLO1 has also been suggested to be involved in anxiety diseases, autism, and Alzheimer's disease.

Molecular Weight: 27 kDa (mouse, 29 kDa (human, simian)

Gene ID: 109801

UniProt: Q9CPU0