TNFRSF12A antibody (AA 61-129)

Catalog No. ABIN741060

This anti-TNFRSF12A antibody is a Rabbit Polyclonal antibody detecting TNFRSF12A in ELISA. Suitable for Mouse and Rat. This Primary Antibody has been cited in 2+ publications.

Quick Overview for TNFRSF12A antibody (AA 61-129) (ABIN741060)

Target: TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFRSF12A antibody is un-conjugated

Application: ELISA

Product Details anti-TNFRSF12A Antibody

Binding Specificity: AA 61-129

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TNFRSF12A

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TNFRSF12A antibody (ABIN741060)

Connolly, Shetty, Stokum, Hoeschele, Siegel, Miller, Kim, Ho, Davila, Simard, Devine, Rossmeisl, Holland, Winkles, Woodworth: "Cross-species transcriptional analysis reveals conserved and host-specific neoplastic processes in mammalian glioma." in: Scientific reports, Vol. 8, Issue 1, pp. 1180, (2018) (PubMed).

Target Details for TNFRSF12A

Target: TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))

Alternative Name: TNFRSF12A

Background:

Synonyms: FN14, CD266, TWEAKR, Tumor necrosis factor receptor superfamily member 12A, Fibroblast growth factor-inducible immediate-early response protein 14, FGF-inducible 14, Tweak-receptor, TNFRSF12A

Background: Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.

Gene ID: 51330

UniProt: Q9NP84

Pathways: Apoptosis, Regulation of Cell Size