GLUT12 antibody (AA 251-350)

Catalog No. ABIN741765

Product Details anti-GLUT12 Antibody

Target: GLUT12 (SLC2A12) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 12 (SLC2A12))

Binding Specificity: AA 251-350

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLUT12 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GLUT12

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-GLUT12 antibody (ABIN741765)

Gil-Iturbe, Castilla-Madrigal, Barrenetxe, Villaro, Lostao: "GLUT12 expression and regulation in murine small intestine and human Caco-2 cells." in: Journal of cellular physiology, Vol. 234, Issue 4, pp. 4396-4408, (2019) (PubMed).

Murakami, Chiba, Tsuboi, Matsumoto, Kawauchi, Fujihara, Mashima, Kanenishi, Yamamoto, Ueno: "Immunoreactivity of glucose transporter 8 is localized in the epithelial cells of the choroid plexus and in ependymal cells." in: Histochemistry and cell biology, Vol. 146, Issue 2, pp. 231-6, (2016) (PubMed).

Pujol-Gimenez, de Heredia, Idoate, Airley, Lostao, Evans: "Could GLUT12 be a Potential Therapeutic Target in Cancer Treatment? A Preliminary Report." in: Journal of Cancer, Vol. 6, Issue 2, pp. 139-43, (2015) (PubMed).

Pujol-Gimenez, Martisova, Perez-Mediavilla, Lostao, Ramirez: "Expression of the glucose transporter GLUT12 in Alzheimer's disease patients." in: Journal of Alzheimer's disease : JAD, Vol. 42, Issue 1, pp. 97-101, (2014) (PubMed).

Target Details for GLUT12

Target: GLUT12 (SLC2A12) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 12 (SLC2A12))

Alternative Name: GLUT12 (SLC2A12 Products)

Synonyms: zgc:66027 antibody, zgc:85776 antibody, SLC2A12 antibody, GLUT12 antibody, GLUT8 antibody, GLUT-12 antibody, Glut12 antibody, glut12 antibody, solute carrier family 2 (facilitated glucose transporter), member 12 antibody, solute carrier family 2 member 12 antibody, solute carrier family 2 (facilitated glucose transporter), member 12 L homeolog antibody, slc2a12 antibody, SLC2A12 antibody, Slc2a12 antibody, slc2a12.L antibody

Background:

Synonyms: GLUT8, GLUT12, Solute carrier family 2, facilitated glucose transporter member 12, Glucose transporter type 12, GLUT-12, SLC2A12

Background: GLUT12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion. Thirteen different types of glucose/fructose transport carrier proteins designated as Glut 1-13 facilitate glucose/fructose transport across the cell membrane. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers.

Gene ID: 154091

UniProt: Q8TD20

Pathways: Warburg Effect