GLUT12 antibody (AA 251-350)

Catalog No. ABIN741765

Cited in 4+ publications. The Rabbit Polyclonal anti-GLUT12 antibody (ABIN741765) specifically detects GLUT12 in WB, FACS, ELISA, IF (cc), IF (p), IHC (fro) and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GLUT12 antibody (AA 251-350) (ABIN741765)

Target: GLUT12 (SLC2A12) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 12 (SLC2A12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLUT12 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GLUT12 Antibody

Binding Specificity: AA 251-350

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GLUT12

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-GLUT12 antibody (ABIN741765)

Gil-Iturbe, Castilla-Madrigal, Barrenetxe, Villaro, Lostao: "GLUT12 expression and regulation in murine small intestine and human Caco-2 cells." in: Journal of cellular physiology, Vol. 234, Issue 4, pp. 4396-4408, (2019) (PubMed).

Murakami, Chiba, Tsuboi, Matsumoto, Kawauchi, Fujihara, Mashima, Kanenishi, Yamamoto, Ueno: "Immunoreactivity of glucose transporter 8 is localized in the epithelial cells of the choroid plexus and in ependymal cells." in: Histochemistry and cell biology, Vol. 146, Issue 2, pp. 231-6, (2016) (PubMed).

Pujol-Gimenez, de Heredia, Idoate, Airley, Lostao, Evans: "Could GLUT12 be a Potential Therapeutic Target in Cancer Treatment? A Preliminary Report." in: Journal of Cancer, Vol. 6, Issue 2, pp. 139-43, (2015) (PubMed).

Pujol-Gimenez, Martisova, Perez-Mediavilla, Lostao, Ramirez: "Expression of the glucose transporter GLUT12 in Alzheimer's disease patients." in: Journal of Alzheimer's disease : JAD, Vol. 42, Issue 1, pp. 97-101, (2014) (PubMed).

Target Details for GLUT12

Target: GLUT12 (SLC2A12) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 12 (SLC2A12))

Alternative Name: GLUT12

Background:

Synonyms: GLUT8, GLUT12, Solute carrier family 2, facilitated glucose transporter member 12, Glucose transporter type 12, GLUT-12, SLC2A12

Background: GLUT12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion. Thirteen different types of glucose/fructose transport carrier proteins designated as Glut 1-13 facilitate glucose/fructose transport across the cell membrane. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers.

Gene ID: 154091

UniProt: Q8TD20

Pathways: Warburg Effect