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CYP1A2 antibody (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2) (AA 221-320) Primary Antibody

CYP1A2 Reactivity: Human, Mouse, Rat ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Pubmed (1)
Catalog No. ABIN742470
$339.90
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 4 to 6 Business Days
  • Target
    CYP1A2
    Binding Specificity
    • 15
    • 11
    • 10
    • 8
    • 8
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-320
    Reactivity
    Human, Mouse, Rat
    Host
    • 58
    • 18
    • 8
    Rabbit
    Clonality
    • 69
    • 15
    Polyclonal
    Conjugate
    • 42
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP1A2 antibody is un-conjugated
    Application
    • 59
    • 42
    • 31
    • 23
    • 21
    • 12
    • 12
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Cytochrome P450 1A2
    Isotype
    IgG
  • Application Notes
    WB 1:300-1000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C
    Expiry Date
    12 months
  • Huang, Duan, Zhao, Gao, Niu, Xu, Li: "Reduction of Aflatoxin B1 Toxicity by Lactobacillus plantarum C88: A Potential Probiotic Strain Isolated from Chinese Traditional Fermented Food "Tofu"." in: PLoS ONE, Vol. 12, Issue 1, pp. e0170109, 2017 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)). Further details: Sample: liver

  • Target
    CYP1A2
    Alternative Name
    Cytochrome P450 1A2 (CYP1A2 Antibody Abstract)
    Synonyms
    CP12, P3-450, P450(PA), CYP1A2, CYPIA2, P450-PM4, Cyp1a1, P450-3, CYPD45, P-450d, RATCYPD45, CYP1A5, CP450, CYP-IA2, cytochrome P450 family 1 subfamily A member 2, cytochrome P450 1A2, cytochrome P450 LM4, cytochrome P450, family 1, subfamily A, polypeptide 2, cytochrome P450, family 1, subfamily a, polypeptide 2, cytochrome P450 1A2-like, CYP1A2, LOC100328937, Cyp1a2, VDBG_06455, LOC101825565, LOC102130662
    Background

    Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.

    Subcellular location: Cytoplasm, Cell membrane

    Synonyms: CP12, P3-450, P450(PA), Cytochrome P450 1A2, CYPIA2, Cytochrome P(3)450, Cytochrome P450 4, Cytochrome P450-P3, CYP1A2

    Gene ID
    1544
    UniProt
    P05177
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