CLPS antibody (AA 1-112)

Catalog No. ABIN7867950

The Mouse Monoclonal anti-CLPS antibody is suitable to detect CLPS in samples from Human. It has been validated for IHC (p).

Quick Overview for CLPS antibody (AA 1-112) (ABIN7867950)

Target: CLPS (Colipase, Pancreatic (CLPS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CLPS antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: CLPS-9901

Product Details anti-CLPS Antibody

Binding Specificity: AA 1-112

Purpose: Colipase Antibody / CLPS (azide and preservative free)

Purification: Protein G affinity

Immunogen: A portion of amino acids 1-112 from human CLPS protein was used as the immunogen for the Colipase antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Colipase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the Colipase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CLPS

Target: CLPS (Colipase, Pancreatic (CLPS))

Alternative Name: Colipase

Background: The lipase gene family belongs to one of the most robust genetic superfamilies found in living organisms, which includes esterases and thioesterases. Members of the AB hydrolase subfamily include Hepatic Lipase (HL), Endothelial Lipase (EL), Lipoprotein Lipase (LPL), Pancreatic Lipase (PL), Gastric Lipase (GL) and LCAT. These family members play a crucial role in the metabolism of lipids. Pancreatic lipase, also designated pancreatic triacylglycerol acyl hydrolase, is important for dietary fat absorption as it hydrolyses triglycerides into diglycerides, monoglycerides and free fatty acids. Colipase, also known as CLPS or pancreatic colipase preproprotein, is a 112 amino acid secreted protein that functions as a cofactor of pancreatic lipase. Necessary for dietary lipid hydrolysis and localizing to pancreatic acinar cells, colipase allows pancreatic lipase to anchor itself to the lipid-water interface of lipid micelles, thereby preventing intestinal bile salts from washing it off.

UniProt: P04118

Pathways: Lipid Metabolism