BASP1 antibody (AA 123-150)

Catalog No. ABIN7870348

The Rabbit Polyclonal anti-BASP1 antibody (ABIN7870348) specifically detects BASP1 in WB. The antibody is reactive with Human samples.

Quick Overview for BASP1 antibody (AA 123-150) (ABIN7870348)

Target: BASP1 (Brain Abundant, Membrane Attached Signal Protein 1 (BASP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BASP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BASP1 Antibody

Binding Specificity: AA 123-150

Purpose: BASP1 Antibody / Brain acid soluble protein 1

Purification: Antigen affinity

Immunogen: A portion of amino acids 123-150 from the human protein was used as the immunogen for this BASP1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the BASP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the BASP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for BASP1

Target: BASP1 (Brain Abundant, Membrane Attached Signal Protein 1 (BASP1))

Alternative Name: BASP1

Background: BASP1, or Brain acid soluble protein 1, and also known as NAP22 or CAP-23, is a highly conserved protein found in the brain and nervous system. It plays a pivotal role in regulating neuronal growth, synaptic plasticity, and cell signaling. BASP1 is known to interact with various cellular proteins and lipids, influencing processes such as axonal growth, neurotransmitter release, and neuroprotection. Research has shown that BASP1 is involved in a multitude of cellular processes that are essential for proper brain function. It plays a crucial role in promoting dendritic branching, axonal outgrowth, and neuronal migration during brain development. Additionally, BASP1 is implicated in regulating the release of neurotransmitters such as dopamine and acetylcholine, which are crucial for cognitive functions. Given its pivotal role in brain function, BASP1 dysregulation has been linked to various neurological disorders. Studies have shown that abnormal levels of BASP1 expression are associated with conditions such as Alzheimer's disease, Parkinson's disease, and schizophrenia.

UniProt: P80723