PUS7L antibody (AA 165-699)

Catalog No. ABIN7871150

This Rabbit Polyclonal antibody specifically detects PUS7L in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PUS7L antibody (AA 165-699) (ABIN7871150)

Target: PUS7L (Pseudouridylate Synthase 7 Homolog-Like (PUS7L))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUS7L antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PUS7L Antibody

Binding Specificity: AA 165-699

Purpose: PUS7L Antibody / Pseudouridylate synthase 7 homolog-like protein

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (R165-H699) was used as the immunogen for the PUS7L antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PUS7L antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PUS7L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PUS7L

Target: PUS7L (Pseudouridylate Synthase 7 Homolog-Like (PUS7L))

Alternative Name: PUS7L

Background: Pseudouridylate synthase 7 homolog-like protein is an enzyme that in humans is encoded by the PUS7L gene. PUS7L (pseudouridylate synthase 7 homolog (S. cerevisiae) -like) is a 701 amino acid protein that belongs to the pseudouridine synthase truD family and contains one TRUD domain. The PUS7L gene is conserved in chimpanzee, canine, bovine, mouse, chicken and zebrafish, and maps to human chromosome 12q12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction.

UniProt: Q9H0K6