TTC8 antibody (AA 271-533)

Catalog No. ABIN7873159

The Rabbit Polyclonal anti-TTC8 antibody (ABIN7873159) specifically detects TTC8 in WB, ELISA and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TTC8 antibody (AA 271-533) (ABIN7873159)

Target: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTC8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-TTC8 Antibody

Binding Specificity: AA 271-533

Purpose: BBS8 Antibody / Bardet-Biedl syndrome 8 / TTC8

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids E271-Q533) was used as the immunogen for the BBS8 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the BBS8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the BBS8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TTC8

Target: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Alternative Name: BBS8

Background: Tetratricopeptide repeat domain 8 (TTC8) also known as Bardet-Biedl syndrome 8 (BBS8) is a protein that in humans is encoded by the TTC8 gene. This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. A mutation in this gene has also been implicated in nonsyndromic retinitis pigmentosa. Alternative splicing results in multiple transcript variants.

UniProt: Q8TAM2

Pathways: Hedgehog Signaling