IDUA antibody (AA 28-634)

Catalog No. ABIN7873280

This Rabbit Polyclonal antibody specifically detects IDUA in ELISA, WB, FACS, IHC (p) and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for IDUA antibody (AA 28-634) (ABIN7873280)

Target: IDUA (Iduronidase, alpha-L- (IDUA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDUA antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-IDUA Antibody

Binding Specificity: AA 28-634

Purpose: IDUA Antibody / Alpha-L-iduronidase

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids A28-D634) was used as the immunogen for the IDUA antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the IDUA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the IDUA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for IDUA

Target: IDUA (Iduronidase, alpha-L- (IDUA))

Alternative Name: IDUA

Background: This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).

UniProt: P35475

Pathways: Glycosaminoglycan Metabolic Process