HGD antibody (AA 374-445)

Catalog No. ABIN7874435

This Mouse Monoclonal antibody specifically detects HGD in WB, IHC (p) and FACS. It exhibits reactivity toward Human.

Quick Overview for HGD antibody (AA 374-445) (ABIN7874435)

Target: HGD (Homogentisate 1,2-Dioxygenase (HGD))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HGD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 2F11E1

Product Details anti-HGD Antibody

Binding Specificity: AA 374-445

Purpose: Homogentisate 1,2-dioxygenase Antibody / HGD

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D374-N445) was used as the immunogen for the Homogentisate 1,2-dioxygenase antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the Homogentisate 1,2-dioxygenase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Homogentisate 1,2-dioxygenase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for HGD

Target: HGD (Homogentisate 1,2-Dioxygenase (HGD))

Alternative Name: Homogentisate 1,2-dioxygenase

Background: The HGD gene encodes homogentisate 1,2-dioxygenase (HGD), an enzyme involved in the catabolism of phenylalanine and tyrosine. This enzyme is involved in the catabolism of the amino acids tyrosine and phenylalanine. Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria. This gene is mapped to chromosome 3q21-q23 by a preliminary PCR screen of hamster/human somatic cell hybrid genomic DNA samples and by fluorescence in situ hybridization.

UniProt: Q93099