SHROOM2 antibody (AA 427-1138)

Catalog No. ABIN7874940

The Rabbit Polyclonal anti-SHROOM2 antibody is suitable to detect SHROOM2 in samples from Human. It has been validated for ELISA, WB and FACS.

Quick Overview for SHROOM2 antibody (AA 427-1138) (ABIN7874940)

Target: SHROOM2 (Shroom Family Member 2 (SHROOM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHROOM2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-SHROOM2 Antibody

Binding Specificity: AA 427-1138

Purpose: SHROOM2 Antibody / APXL

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R427-H1138) was used as the immunogen for the SHROOM2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SHROOM2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SHROOM2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SHROOM2

Target: SHROOM2 (Shroom Family Member 2 (SHROOM2))

Alternative Name: SHROOM2

Background: Shroom family member 2 is a protein that in humans is encoded by the SHROOM2 gene. This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene.

UniProt: Q13796

Pathways: Cell-Cell Junction Organization, Asymmetric Protein Localization