ALDOA antibody (AA 50-364)

Catalog No. ABIN7875405

The Rabbit Polyclonal anti-ALDOA antibody is suitable to detect ALDOA in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, FACS and IHC (p).

Quick Overview for ALDOA antibody (AA 50-364) (ABIN7875405)

Target: ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDOA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ALDOA Antibody

Binding Specificity: AA 50-364

Purpose: Aldolase A Antibody / ALDOA

Purification: Affinity purified

Immunogen: A human recombinant protein (amino acids E50-Y364) was used as the immunogen for the Aldolase A antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Aldolase A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Aldolase A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ALDOA

Target: ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Alternative Name: Aldolase A

Background: Aldolase A (ALDOA, or ALDA), also known as fructose-bisphosphate aldolase, is an enzyme that in humans is encoded by the ALDOA gene on chromosome 16. This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10.

UniProt: P04075

Pathways: Ribonucleoside Biosynthetic Process