DRD4 antibody (AA 57-387)

Catalog No. ABIN7875806

This Rabbit Polyclonal antibody specifically detects DRD4 in WB, ELISA and FACS. It exhibits reactivity toward Mouse and Rat.

Quick Overview for DRD4 antibody (AA 57-387) (ABIN7875806)

Target: DRD4 (Dopamine Receptor D4 (DRD4))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRD4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-DRD4 Antibody

Binding Specificity: AA 57-387

Purpose: Drd4 Antibody

Purification: Affinity purified

Immunogen: Recombinant mouse protein (amino acids A57-C387) was used as the immunogen for the Drd4 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Drd4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Drd4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for DRD4

Target: DRD4 (Dopamine Receptor D4 (DRD4))

Alternative Name: Drd4

Background: D(4) dopamine receptor is aproteinthat in humans is encoded by the Drd4gene. This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. And this subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P51436

Pathways: cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity