DTNA antibody (AA 692-721)

Catalog No. ABIN7876457

This Rabbit Polyclonal antibody specifically detects DTNA in WB, IF and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for DTNA antibody (AA 692-721) (ABIN7876457)

Target: DTNA (Dystrobrevin alpha (DTNA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTNA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DTNA Antibody

Binding Specificity: AA 692-721

Purpose: Dystrobrevin alpha Antibody / DTNA

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 692-721 from the human protein was used as the immunogen for the Dystrobrevin alpha antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Dystrobrevin alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Dystrobrevin alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for DTNA

Target: DTNA (Dystrobrevin alpha (DTNA))

Alternative Name: Dystrobrevin alpha

Background: The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

UniProt: Q9Y4J8