APOE antibody (AA 95-222)

Catalog No. ABIN7877220

The Rabbit Polyclonal anti-APOE antibody is suitable to detect APOE in samples from Human. It has been validated for WB, ELISA, IF and FACS.

Quick Overview for APOE antibody (AA 95-222) (ABIN7877220)

Target: APOE (Apolipoprotein E (APOE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOE antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-APOE Antibody

Binding Specificity: AA 95-222

Purpose: Apolipoprotein E Antibody / APOE

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids E95-Q222) was used as the immunogen for the Apolipoprotein E antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Apolipoprotein E antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Apolipoprotein E antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for APOE

Target: APOE (Apolipoprotein E (APOE))

Alternative Name: Apolipoprotein E

Background: Apolipoprotein E is also known as APOE, AD2 or LPG. The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants.

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism