CD27 antibody (full length)

Catalog No. ABIN7877852

This Mouse Monoclonal antibody specifically detects CD27 in FACS, ELISA, IF and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CD27 antibody (full length) (ABIN7877852)

Target: CD27 (CD27 Molecule (CD27))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD27 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: LPFS2-1611

Product Details anti-CD27 Antibody

Binding Specificity: full length

Purpose: CD27 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A recombinant full-length human CD27 protein was used as the immunogen for this CD27 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the CD27 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the CD27 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CD27

Target: CD27 (CD27 Molecule (CD27))

Alternative Name: CD27

Background: Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.

UniProt: P26842

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints